@article {156071,
	title = {Milk Bioactives May Manipulate Microbes to Mediate Parent-Offspring Conflict},
	journal = {Evol Med Public Health},
	year = {2015},
	note = {<p>Evol Med Public Health 2015 Apr 2. 10.1093/emph/eov007</p>
},
	month = {04/2015},
	pages = {eov007},
	abstract = {<p>Among mammals, milk constituents directly influence the ecology of the infant{\textquoteright}s commensal microbiota. The immunological and nutritional impacts of breast milk and microbiota are increasingly well-understood; less clear are the consequences for infant behavior. Here we propose that interactions among bioactives in mother{\textquoteright}s milk and microbes in the infant gut contribute to infant behavioral phenotype and, in part, have the potential to mediate parent-offspring conflict. We hypothesize that infant behavior likely varies as a function of their mother{\textquoteright}s milk composition interacting with the infant{\textquoteright}s neurobiology directly and indirectly through the commensal gut bacteria. In this paper, we will explore our hypothesis of a milk-microbiota-brain-behavior dynamic in the context of the co-evolution between human milk oligosaccharides (HMO), bacteria, the gut-brain axis, and behavior. Integrating established features of these systems allows us to generate novel hypotheses to motivate future research and consider potential implications of current and emerging clinical treatments.</p>
},
	url = {http://emph.oxfordjournals.org/content/early/2015/04/01/emph.eov007.long},
	author = {Allen-Blevins, C.R. and Sela, D.A. and Hinde, K.}
}
