@book {1858,
	title = {Biological basis of substance abuse},
	year = {1993},
	note = {edited by Stanley G. Korenman, Jack D. Barchasill. ; 25 cm},
	pages = {xvii, 516 p},
	publisher = {Oxford University Press},
	organization = {Oxford University Press},
	address = {New York},
	abstract = {This volume describes our current understanding of the biological mechanisms in the central nervous system of nicotine, alcohol, cocaine, heroin, marijuana, and other drugs of abuse. Organized to focus on the similarities rather than the differences between drug actions, the processes undergo examination by level of cellular organization rather than by substance. The book proceeds from characterization of drug effects in relation to neurotransmitters and their receptors, through localization of drug effects in the brain in relation to specific anatomic structures. The impact of local stimulation or lesions on animal behaviors with respect to reward, reinforcement, desensitization and sensitization receive attention. Human genetic studies and therapeutic trials of addiction management complete the presentations.Neurobiology of addiction: an integrative view / Floyd E. Bloom -- Molecular mechanisms in opiate addiction: a model for the study of substance abuse / Mark von Zastrow ... [et al.] -- Diversity among the opioid receptors / Christopher J. Evans -- Second-messenger and protein phosphorylation mechanisms underlying opiate and cocaine addiction / Eric J. Nestler, Xavier Guitart and Dana Beitner-Johnson -- Cocaine receptor: properties and significance / Michael J. Kuhar ... [et al.] -- Pharmacological diversity of nicotine receptors / James W. Patrick and Charles W. Luetje -- THC receptor and its implications / Lisa A. Matsuda ... [et al.] -- Mechanisms of action of the steroid receptor superfamily of gene regulatory proteins / Bert W. O{\textquoteright}Malley -- Drug reward and brain circuitry: recent advances and future directions / Keith A. Trujillo ... [et al.] -- Cellular basis of opioid action / R.A. North -- Cellular mechanisms of cocaine action: effects in brain slice preparations / Thomas V. Dunwiddie and Mark S. Brodie -- Cocaine and monoamine neurons / Francis J. White and Benjamin S. Bunney(cont) Localization of cannabinoid receptors in brain: relationship to motor and reward systems / Miles A. Herkenham -- Effects of cannabinoids and nicotine on central nervous system neurons / Sam A. Deadwyler ... [et al.] -- Long-term potentiation of synaptic transmission / Robert C. Malenka -- Neurochemical circuitry of drug abuse: the potential of in vivo microdialysis / Nigel T. Maidment and Magali Bertolucci -- Mammalian morphine alkaloids: identification and possible in vivo biosynthesis / Kym F. Faull -- Neurochemical substrates underlying the mechanism of action of phencyclidine (PCP) / Robert N. Pechnick -- Ice: d-methamphetamine hydrochloride / Arthur K. Cho -- Neuropharmacology of ethanol / Steven J. Henriksen -- Opiates/opioids and reinforcement / Steven I. Dworkin and James E. Smith -- Reward system and cocaine abuse / George F. Koob -- Paranoid psychosis following continuous amphetamine or cocaine: relationship to selective neurotoxicity / Gaylord D. Ellison -- Persistent sensitizing effects of drugs on brain dopamine systems and behavior: implications for addiction and relapse / Terry E. Robinson(cont) Genetic risk factors in susceptibility to substance abuse / C. Robert Cloninger and Stephen H. Dinwiddie -- Brain electrophysiology in subjects at risk for alcoholism / Henri Begleiter and Bernice Porjesz -- Cocaine addiction: psychology, neurophysiology, and treatment / Frank H. Gawin -- Carbamazepine in the treatment of cocaine abuse / Robert M. Post, Susan R.B. Weiss and Thomas G. Aigner -- Buprenorphine{\textquoteright}s effects on cocaine and heroin abuse / Nancy K. Mello and Jack H. Mendelson -- Effectiveness of treatment for substance abuse / Charles P. O{\textquoteright}Brien, A. Thomas McLellan and Arthur Alterman},
	keywords = {Brain, Drug, Drug abuse, Receptors, Substance abuse},
	isbn = {0195071549 (alk. paper)},
	author = {Korenman, Stanley G and Barchas, Jack D}
}
