@article {309999,
	title = {A draft sequence of the Neandertal genome.},
	journal = {Science},
	volume = {328},
	year = {2010},
	month = {2010 May 7},
	pages = {710-22},
	abstract = {<p>Neandertals, the closest evolutionary relatives of present-day humans, lived in large parts of Europe and western Asia before disappearing 30,000 years ago. We present a draft sequence of the Neandertal genome composed of more than 4 billion nucleotides from three individuals. Comparisons of the Neandertal genome to the genomes of five present-day humans from different parts of the world identify a number of genomic regions that may have been affected by positive selection in ancestral modern humans, including genes involved in metabolism and in cognitive and skeletal development. We show that Neandertals shared more genetic variants with present-day humans in Eurasia than with present-day humans in sub-Saharan Africa, suggesting that gene flow from Neandertals into the ancestors of non-Africans occurred before the divergence of Eurasian groups from each other.</p>
},
	keywords = {African Continental Ancestry Group, Animals, Asian Continental Ancestry Group, Base Sequence, Bone and Bones, DNA, Mitochondrial, European Continental Ancestry Group, Evolution, Molecular, Extinction, Biological, Female, Fossils, Gene Dosage, Gene Flow, Genetic Variation, Genome, Genome, Human, Haplotypes, Hominidae, Humans, Pan troglodytes, Polymorphism, Single Nucleotide, Selection, Genetic, Sequence Alignment, Sequence Analysis, DNA, Time},
	issn = {1095-9203},
	doi = {10.1126/science.1188021},
	author = {Green, Richard E and Krause, Johannes and Briggs, Adrian W and Maricic, Tomislav and Stenzel, Udo and Kircher, Martin and Patterson, Nick and Li, Heng and Zhai, Weiwei and Fritz, Markus Hsi-Yang and Hansen, Nancy F and Durand, Eric Y and Malaspinas, Anna-Sapfo and Jensen, Jeffrey D and Marques-Bonet, Tomas and Alkan, Can and Pr{\"u}fer, Kay and Meyer, Matthias and Burbano, Hern{\'a}n A and Good, Jeffrey M and Schultz, Rigo and Aximu-Petri, Ayinuer and Butthof, Anne and H{\"o}ber, Barbara and H{\"o}ffner, Barbara and Siegemund, Madlen and Weihmann, Antje and Nusbaum, Chad and Lander, Eric S and Russ, Carsten and Novod, Nathaniel and Affourtit, Jason and Egholm, Michael and Verna, Christine and Rudan, Pavao and Brajkovic, Dejana and Kucan, Zeljko and Gusic, Ivan and Doronichev, Vladimir B and Golovanova, Liubov V and Lalueza-Fox, Carles and de la Rasilla, Marco and Fortea, Javier and Rosas, Antonio and Schmitz, Ralf W and Johnson, Philip L F and Eichler, Evan E and Falush, Daniel and Birney, Ewan and Mullikin, James C and Slatkin, Montgomery and Nielsen, Rasmus and Kelso, Janet and Lachmann, Michael and Reich, David and P{\"a}{\"a}bo, Svante}
}
