@article {315680,
	title = {Rotating waves during human sleep spindles organize global patterns of activity that repeat precisely through the night.},
	journal = {Elife},
	volume = {5},
	year = {2016},
	month = {11 15},
	abstract = {During sleep, the thalamus generates a characteristic pattern of transient, 11-15 Hz sleep spindle oscillations, which synchronize the cortex through large-scale thalamocortical loops. Spindles have been increasingly demonstrated to be critical for sleep-dependent consolidation of memory, but the specific neural mechanism for this process remains unclear. We show here that cortical spindles are spatiotemporally organized into circular wave-like patterns, organizing neuronal activity over tens of milliseconds, within the timescale for storing memories in large-scale networks across the cortex via spike-time dependent plasticity. These circular patterns repeat over hours of sleep with millisecond temporal precision, allowing reinforcement of the activity patterns through hundreds of reverberations. These results provide a novel mechanistic account for how global sleep oscillations and synaptic plasticity could strengthen networks distributed across the cortex to store coherent and integrated memories.},
	isbn = {2050-084X},
	url = {https://www.ncbi.nlm.nih.gov/pubmed/27855061},
	author = {Muller, L and Piantoni, G and Koller, D and Cash, SS and Halgren, E and Sejnowski, TJ}
}
