@article {320971,
	title = {Coupling of methyl coenzyme M reduction with carbon dioxide activation in extracts of Methanobacterium thermoautotrophicum.},
	journal = {J Bacteriol},
	volume = {152},
	year = {1982},
	month = {1982 Nov},
	pages = {840-7},
	abstract = {<p>The stimulation of carbon dioxide reduction to methane by addition of 2-(methylthio)ethanesulfonate (CH3-S-CoM) to cell extracts of Methanobacterium thermoautotrophicum was investigated. Similar stimulation of CO2 reduction by CH3-S-CoM was found for cell extracts of Methanobacterium bryantii and Methanospirillum hungatei. The CH3-S-CoM requirement could be met by the methanogenic precursors formaldehyde, serine, or pyruvate, or by 2-(ethylthio)ethanesulfonate (CH3CH2-S-CoM), but not by other coenzyme M derivatives. Efficient reduction of CO2 to CH4 was favored by low concentrations of CH3-S-CoM and high concentrations of CO2. Sulfhydryl compounds were identified as effective inhibitors of CO2 reduction. Both an allosteric model and a free-radical model for the mechanism of CO2 activation and reduction are discussed.</p>
},
	keywords = {Carbon Dioxide, Euryarchaeota, Kinetics, Mercaptoethanol, Mesna, Oxidation-Reduction, Species Specificity},
	issn = {0021-9193},
	doi = {10.1038/s41467-019-12764-8},
	author = {Romesser, J A and Wolfe, R S}
}
