@article {327076,
	title = {Codiversification of gut microbiota with humans.},
	journal = {Science},
	volume = {377},
	year = {2022},
	month = {2022 Sep 16},
	pages = {1328-1332},
	abstract = {<p>The gut microbiomes of human populations worldwide have many core microbial species in common. However, within a species, some strains can show remarkable population specificity. The question is whether such specificity arises from a shared evolutionary history (codiversification) between humans and their microbes. To test for codiversification of host and microbiota, we analyzed paired gut metagenomes and human genomes for 1225 individuals in Europe, Asia, and Africa, including mothers and their children. Between and within countries, a parallel evolutionary history was evident for humans and their gut microbes. Moreover, species displaying the strongest codiversification independently evolved traits characteristic of host dependency, including reduced genomes and oxygen and temperature sensitivity. These findings all point to the importance of understanding the potential role of population-specific microbial strains in microbiome-mediated disease phenotypes.</p>
},
	keywords = {Bacteria, Child, Gastrointestinal Microbiome, Host Microbial Interactions, Humans, Metagenome, Oxygen},
	issn = {1095-9203},
	doi = {10.1126/science.abm7759},
	url = {https://www.science.org/doi/10.1126/science.abm7759?url_ver=Z39.88-2003\&rfr_id=ori:rid:crossref.org\&rfr_dat=cr_pub\%20\%200pubmed},
	author = {Suzuki, Taichi A and Fitzstevens, J Liam and Schmidt, Victor T and Enav, Hagay and Huus, Kelsey E and Mbong Ngwese, Mirabeau and Grie{\ss}hammer, Anne and Pfleiderer, Anne and Adegbite, Bayode R and Zinsou, Jeannot F and Esen, Meral and Velavan, Thirumalaisamy P and Adegnika, Ayola A and Song, Le Huu and Spector, Timothy D and Muehlbauer, Amanda L and Marchi, Nina and Kang, Hyena and Maier, Lisa and Blekhman, Ran and S{\'e}gurel, Laure and Ko, GwangPyo and Youngblut, Nicholas D and Kremsner, Peter and Ley, Ruth E}
}
