@article {329029,
	title = {A global catalog of whole-genome diversity from 233 primate species.},
	journal = {Science},
	volume = {380},
	year = {2023},
	month = {2023 Jun 02},
	pages = {906-913},
	abstract = {<p>The rich diversity of morphology and behavior displayed across primate species provides an informative context in which to study the impact of genomic diversity on fundamental biological processes. Analysis of that diversity provides insight into long-standing questions in evolutionary and conservation biology and is urgent given severe threats these species are facing. Here, we present high-coverage whole-genome data from 233 primate species representing 86\% of genera and all 16 families. This dataset was used, together with fossil calibration, to create a nuclear DNA phylogeny and to reassess evolutionary divergence times among primate clades. We found within-species genetic diversity across families and geographic regions to be associated with climate and sociality, but not with extinction risk. Furthermore, mutation rates differ across species, potentially influenced by effective population sizes. Lastly, we identified extensive recurrence of missense mutations previously thought to be human specific. This study will open a wide range of research avenues for future primate genomic research.</p>
},
	keywords = {Animals, Biological Evolution, Genetic Variation, Genome, Humans, Mutation Rate, Phylogeny, Population Density, Primates},
	issn = {1095-9203},
	doi = {10.1126/science.abn7829},
	author = {Kuderna, Lukas F K and Gao, Hong and Janiak, Mareike C and Kuhlwilm, Martin and Orkin, Joseph D and Bataillon, Thomas and Manu, Shivakumara and Valenzuela, Alejandro and Bergman, Juraj and Rousselle, Marjolaine and Silva, Felipe Ennes and Agueda, Lidia and Blanc, Julie and Gut, Marta and de Vries, Dorien and Goodhead, Ian and Harris, R Alan and Raveendran, Muthuswamy and Jensen, Axel and Chuma, Idrissa S and Horvath, Julie E and Hvilsom, Christina and Juan, David and Frandsen, Peter and Schraiber, Joshua G and de Melo, Fabiano R and Bertuol, Fabr{\'\i}cio and Byrne, Hazel and Sampaio, Iracilda and Farias, Izeni and Valsecchi, Jo{\~a}o and Messias, Malu and da Silva, Maria N F and Trivedi, Mihir and Rossi, Rogerio and Hrbek, Tomas and Andriaholinirina, Nicole and Rabarivola, Cl{\'e}ment J and Zaramody, Alphonse and Jolly, Clifford J and Phillips-Conroy, Jane and Wilkerson, Gregory and Abee, Christian and Simmons, Joe H and Fernandez-Duque, Eduardo and Kanthaswamy, Sree and Shiferaw, Fekadu and Wu, Dongdong and Zhou, Long and Shao, Yong and Zhang, Guojie and Keyyu, Julius D and Knauf, Sascha and Le, Minh D and Lizano, Esther and Merker, Stefan and Navarro, Arcadi and Nadler, Tilo and Khor, Chiea Chuen and Lee, Jessica and Tan, Patrick and Lim, Weng Khong and Kitchener, Andrew C and Zinner, Dietmar and Gut, Ivo and Melin, Amanda D and Guschanski, Katerina and Schierup, Mikkel Heide and Beck, Robin M D and Umapathy, Govindhaswamy and Roos, Christian and Boubli, Jean P and Rogers, Jeffrey and Farh, Kyle Kai-How and Marques Bonet, Tomas}
}
