<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Olson, M. V.</style></author><author><style face="normal" font="default" size="100%">Ajit Varki</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Sequencing the chimpanzee genome: insights into human evolution and disease</style></title><secondary-title><style face="normal" font="default" size="100%">Nat Rev Genet</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Nature reviews. Genetics</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">*Biological Evolution</style></keyword><keyword><style  face="normal" font="default" size="100%">*Genetic Diseases</style></keyword><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Gene Expression Regulation</style></keyword><keyword><style  face="normal" font="default" size="100%">Genetic Predisposition to Disease</style></keyword><keyword><style  face="normal" font="default" size="100%">Genome</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Inborn</style></keyword><keyword><style  face="normal" font="default" size="100%">Pan troglodytes/*genetics</style></keyword><keyword><style  face="normal" font="default" size="100%">Phenotype</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2003</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Jan</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/12509750</style></url></web-urls></urls><number><style face="normal" font="default" size="100%">1</style></number><edition><style face="normal" font="default" size="100%">2003/01/02</style></edition><volume><style face="normal" font="default" size="100%">4</style></volume><pages><style face="normal" font="default" size="100%">20-28</style></pages><isbn><style face="normal" font="default" size="100%">1471-0056 (Print)1471-00</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Large-scale sequencing of the chimpanzee genome is now imminent. Beyond the inherent fascination of comparing the sequence of the human genome with that of our closest living relative, this project is likely to yield tangible scientific benefits in two areas. First, the discovery of functionally important mutations that are specific to the human lineage offers a new path towards medical benefits. Second, chimpanzee-human comparisons are likely to yield molecular insights into how new biological characteristics evolve--findings that might be relevant throughout the tree of life.&lt;/p&gt;</style></abstract><work-type><style face="normal" font="default" size="100%">Review</style></work-type><accession-num><style face="normal" font="default" size="100%">12509750 PMID</style></accession-num><notes><style face="normal" font="default" size="100%">&lt;p&gt;EnglandNat Rev Genet. 2003 Jan;4(1):20-8.&lt;/p&gt;</style></notes><auth-address><style face="normal" font="default" size="100%">University of Washington Genome Center, Department of Medicine, University of Washington, Seattle, Washington 98195, USA. mvo@u.washington.edu</style></auth-address></record></records></xml>