<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Denton, DA</style></author><author><style face="normal" font="default" size="100%">Blair West JR</style></author><author><style face="normal" font="default" size="100%">McBurnie, MI</style></author><author><style face="normal" font="default" size="100%">Miller, JA</style></author><author><style face="normal" font="default" size="100%">Weisinger, RS</style></author><author><style face="normal" font="default" size="100%">Williams, RM</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effect of adrenocorticotrophic hormone on sodium appetite in mice.</style></title><secondary-title><style face="normal" font="default" size="100%">Am J Physiol Regul Integr Comp Physiol</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Adrenocorticotropic Hormone/blood/pharmacology/*physiology</style></keyword><keyword><style  face="normal" font="default" size="100%">Angiotensin-Converting Enzyme Inhibitors/pharmacology</style></keyword><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Appetite/drug effects/*physiology</style></keyword><keyword><style  face="normal" font="default" size="100%">Captopril/pharmacology</style></keyword><keyword><style  face="normal" font="default" size="100%">Corticotropin-Releasing Hormone/pharmacology</style></keyword><keyword><style  face="normal" font="default" size="100%">Cosyntropin/pharmacology</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">1999</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Oct</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/10516242</style></url></web-urls></urls><number><style face="normal" font="default" size="100%">4 Pt 2</style></number><publisher><style face="normal" font="default" size="100%">UNITED STATES</style></publisher><volume><style face="normal" font="default" size="100%">277</style></volume><pages><style face="normal" font="default" size="100%">R1033-40</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;A main vector of the effects of stress is secretion of corticotrophin releasing factor (CRF), adrenocorticotrophin (ACTH), and adrenal steroids. Systemic administration of ACTH (2.8 microgram/day sc) for 7 days in BALB/c mice caused a very large increase of voluntary intake of 0.3 M NaCl equivalent to turnover of total body sodium content each day. Intracerebroventricular infusion of ACTH (20 ng/day) had no effect. Intracerebroventricular infusion of ovine CRF (10 ng/h for 7 days) caused an increase of sodium intake. The large sodium appetite-stimulating effect of systemic ACTH was not influenced by concurrent systemic infusion of captopril (2 mg/day). Induction of stress by immobilization of mice on a running wheel caused an increase in Na appetite associated with a 50% decrease of thymus weight, indicative of corticosteroid effects. The present data suggest that stress and the hormone cascade initiated by stress evoke a large sodium appetite in mice, which may be an important survival mechanism in environmental conditions causing stress.&lt;/p&gt;</style></abstract><accession-num><style face="normal" font="default" size="100%">10516242</style></accession-num><notes><style face="normal" font="default" size="100%">&lt;p&gt;Am J Physiol. 1999 Oct;277(4 Pt 2):R1033-40.&lt;/p&gt;</style></notes><auth-address><style face="normal" font="default" size="100%">Howard Florey Institute of Experimental Physiology and Medicine, Parkville, Victoria 3052, Australia 3052. d.denton@hfi.unimelb.edu.au</style></auth-address></record></records></xml>