<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sanders, A R</style></author><author><style face="normal" font="default" size="100%">Martin, E R</style></author><author><style face="normal" font="default" size="100%">Beecham, G W</style></author><author><style face="normal" font="default" size="100%">Guo, S</style></author><author><style face="normal" font="default" size="100%">Dawood, K</style></author><author><style face="normal" font="default" size="100%">Rieger, G</style></author><author><style face="normal" font="default" size="100%">Badner, J A</style></author><author><style face="normal" font="default" size="100%">Gershon, E S</style></author><author><style face="normal" font="default" size="100%">Krishnappa, R S</style></author><author><style face="normal" font="default" size="100%">Kolundzija, A B</style></author><author><style face="normal" font="default" size="100%">Duan, J</style></author><author><style face="normal" font="default" size="100%">Gejman, P V</style></author><author><style face="normal" font="default" size="100%">Bailey, J M</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Genome-wide scan demonstrates significant linkage for male sexual orientation.</style></title><secondary-title><style face="normal" font="default" size="100%">Psychol Med</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Psychol Med</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Adult</style></keyword><keyword><style  face="normal" font="default" size="100%">Chromosomes, Human, Pair 8</style></keyword><keyword><style  face="normal" font="default" size="100%">Chromosomes, Human, X</style></keyword><keyword><style  face="normal" font="default" size="100%">Genetic Linkage</style></keyword><keyword><style  face="normal" font="default" size="100%">Genome-Wide Association Study</style></keyword><keyword><style  face="normal" font="default" size="100%">Homosexuality, Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Siblings</style></keyword><keyword><style  face="normal" font="default" size="100%">United States</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2015 May</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/25399360</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">45</style></volume><pages><style face="normal" font="default" size="100%">1379-88</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;b&gt;BACKGROUND: &lt;/b&gt;Findings from family and twin studies support a genetic contribution to the development of sexual orientation in men. However, previous studies have yielded conflicting evidence for linkage to chromosome Xq28.&lt;/p&gt;&lt;p&gt;&lt;b&gt;METHOD: &lt;/b&gt;We conducted a genome-wide linkage scan on 409 independent pairs of homosexual brothers (908 analyzed individuals in 384 families), by far the largest study of its kind to date.&lt;/p&gt;&lt;p&gt;&lt;b&gt;RESULTS: &lt;/b&gt;We identified two regions of linkage: the pericentromeric region on chromosome 8 (maximum two-point LOD = 4.08, maximum multipoint LOD = 2.59), which overlaps with the second strongest region from a previous separate linkage scan of 155 brother pairs; and Xq28 (maximum two-point LOD = 2.99, maximum multipoint LOD = 2.76), which was also implicated in prior research.&lt;/p&gt;&lt;p&gt;&lt;b&gt;CONCLUSIONS: &lt;/b&gt;Results, especially in the context of past studies, support the existence of genes on pericentromeric chromosome 8 and chromosome Xq28 influencing development of male sexual orientation.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">7</style></issue><notes><style face="normal" font="default" size="100%">http://journals.cambridge.org/action/displayFulltext?type=6&amp;fid=9385647&amp;jid=PSM&amp;volumeId=-1&amp;issueId=-1&amp;aid=9385646&amp;bodyId=&amp;membershipNumber=&amp;societyETOCSession=&amp;fulltextType=RA&amp;fileId=S0033291714002451</style></notes><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/25399360?dopt=Abstract</style></custom1></record></records></xml>