<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Willsey, A Jeremy</style></author><author><style face="normal" font="default" size="100%">Sanders, Stephan J</style></author><author><style face="normal" font="default" size="100%">Li, Mingfeng</style></author><author><style face="normal" font="default" size="100%">Dong, Shan</style></author><author><style face="normal" font="default" size="100%">Tebbenkamp, Andrew T</style></author><author><style face="normal" font="default" size="100%">Muhle, Rebecca A</style></author><author><style face="normal" font="default" size="100%">Reilly, Steven K</style></author><author><style face="normal" font="default" size="100%">Lin, Leon</style></author><author><style face="normal" font="default" size="100%">Fertuzinhos, Sofia</style></author><author><style face="normal" font="default" size="100%">Miller, Jeremy A</style></author><author><style face="normal" font="default" size="100%">Murtha, Michael T</style></author><author><style face="normal" font="default" size="100%">Bichsel, Candace</style></author><author><style face="normal" font="default" size="100%">Niu, Wei</style></author><author><style face="normal" font="default" size="100%">Cotney, Justin</style></author><author><style face="normal" font="default" size="100%">Ercan-Sencicek, A Gulhan</style></author><author><style face="normal" font="default" size="100%">Gockley, Jake</style></author><author><style face="normal" font="default" size="100%">Gupta, Abha R</style></author><author><style face="normal" font="default" size="100%">Han, Wenqi</style></author><author><style face="normal" font="default" size="100%">He, Xin</style></author><author><style face="normal" font="default" size="100%">Hoffman, Ellen J</style></author><author><style face="normal" font="default" size="100%">Klei, Lambertus</style></author><author><style face="normal" font="default" size="100%">Lei, Jing</style></author><author><style face="normal" font="default" size="100%">Liu, Wenzhong</style></author><author><style face="normal" font="default" size="100%">Liu, Li</style></author><author><style face="normal" font="default" size="100%">Lu, Cong</style></author><author><style face="normal" font="default" size="100%">Xu, Xuming</style></author><author><style face="normal" font="default" size="100%">Zhu, Ying</style></author><author><style face="normal" font="default" size="100%">Mane, Shrikant M</style></author><author><style face="normal" font="default" size="100%">Lein, Ed S</style></author><author><style face="normal" font="default" size="100%">Wei, Liping</style></author><author><style face="normal" font="default" size="100%">Noonan, James P</style></author><author><style face="normal" font="default" size="100%">Roeder, Kathryn</style></author><author><style face="normal" font="default" size="100%">Devlin, Bernie</style></author><author><style face="normal" font="default" size="100%">Sestan, Nenad</style></author><author><style face="normal" font="default" size="100%">State, Matthew W</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism.</style></title><secondary-title><style face="normal" font="default" size="100%">Cell</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Cell</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Brain</style></keyword><keyword><style  face="normal" font="default" size="100%">Child Development Disorders, Pervasive</style></keyword><keyword><style  face="normal" font="default" size="100%">Exome</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Fetus</style></keyword><keyword><style  face="normal" font="default" size="100%">Gene Expression Profiling</style></keyword><keyword><style  face="normal" font="default" size="100%">Genetic Predisposition to Disease</style></keyword><keyword><style  face="normal" font="default" size="100%">Genome-Wide Association Study</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Mice</style></keyword><keyword><style  face="normal" font="default" size="100%">Mutation</style></keyword><keyword><style  face="normal" font="default" size="100%">Neurons</style></keyword><keyword><style  face="normal" font="default" size="100%">Prefrontal Cortex</style></keyword><keyword><style  face="normal" font="default" size="100%">Sequence Analysis, DNA</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2013</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2013 Nov 21</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/24267886</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">155</style></volume><pages><style face="normal" font="default" size="100%">997-1007</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Autism spectrum disorder (ASD) is a complex developmental syndrome of unknown etiology. Recent studies employing exome- and genome-wide sequencing have identified nine high-confidence ASD (hcASD) genes. Working from the hypothesis that ASD-associated mutations in these biologically pleiotropic genes will disrupt intersecting developmental processes to contribute to a common phenotype, we have attempted to identify time periods, brain regions, and cell types in which these genes converge. We have constructed coexpression networks based on the hcASD &quot;seed&quot; genes, leveraging a rich expression data set encompassing multiple human brain regions across human development and into adulthood. By assessing enrichment of an independent set of probable ASD (pASD) genes, derived from the same sequencing studies, we demonstrate a key point of convergence in midfetal layer 5/6 cortical projection neurons. This approach informs when, where, and in what cell types mutations in these specific genes may be productively studied to clarify ASD pathophysiology.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><notes><style face="normal" font="default" size="100%">http://www.cell.com/retrieve/pii/S0092867413012968</style></notes><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/24267886?dopt=Abstract</style></custom1></record></records></xml>