<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Yu, Fuli</style></author><author><style face="normal" font="default" size="100%">Hill, R Sean</style></author><author><style face="normal" font="default" size="100%">Schaffner, Stephen F</style></author><author><style face="normal" font="default" size="100%">Sabeti, Pardis C</style></author><author><style face="normal" font="default" size="100%">Wang, Eric T</style></author><author><style face="normal" font="default" size="100%">Mignault, Andre A</style></author><author><style face="normal" font="default" size="100%">Ferland, Russell J</style></author><author><style face="normal" font="default" size="100%">Moyzis, Robert K</style></author><author><style face="normal" font="default" size="100%">Walsh, Christopher A</style></author><author><style face="normal" font="default" size="100%">Reich, David</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Comment on &quot;Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens&quot;.</style></title><secondary-title><style face="normal" font="default" size="100%">Science</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Science</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Adaptation, Biological</style></keyword><keyword><style  face="normal" font="default" size="100%">African Continental Ancestry Group</style></keyword><keyword><style  face="normal" font="default" size="100%">Asian Continental Ancestry Group</style></keyword><keyword><style  face="normal" font="default" size="100%">Biological Evolution</style></keyword><keyword><style  face="normal" font="default" size="100%">Brain</style></keyword><keyword><style  face="normal" font="default" size="100%">European Continental Ancestry Group</style></keyword><keyword><style  face="normal" font="default" size="100%">Gene Frequency</style></keyword><keyword><style  face="normal" font="default" size="100%">Haplotypes</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Nerve Tissue Proteins</style></keyword><keyword><style  face="normal" font="default" size="100%">Polymorphism, Single Nucleotide</style></keyword><keyword><style  face="normal" font="default" size="100%">Recombination, Genetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Selection, Genetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Sequence Analysis, DNA</style></keyword><keyword><style  face="normal" font="default" size="100%">Time</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2007</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2007 Apr 20</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">316</style></volume><pages><style face="normal" font="default" size="100%">370</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Mekel-Bobrov et al. (Reports, 9 September 2005, p. 1720) suggested that ASPM, a gene associated with microcephaly, underwent natural selection within the last 500 to 14,100 years. Their analyses based on comparison with computer simulations indicated that ASPM had an unusual pattern of variation. However, when we compare ASPM empirically to a large number of other loci, its variation is not unusual and does not support selection.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5823</style></issue><custom1><style face="normal" font="default" size="100%">&lt;p&gt;http://www.ncbi.nlm.nih.gov/pubmed/17446375?dopt=Abstract&lt;/p&gt;
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