<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Debyser, Isolde W. J.</style></author><author><style face="normal" font="default" size="100%">Soma, Hiroaki</style></author><author><style face="normal" font="default" size="100%">Zwart, Peernel</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Partial hydatidiform mole in a pregnant chimpanzee (Pan troglodytes)</style></title><secondary-title><style face="normal" font="default" size="100%">Zoo Biology</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">DNA ploidy analysis</style></keyword><keyword><style  face="normal" font="default" size="100%">hCG-SP1 assay</style></keyword><keyword><style  face="normal" font="default" size="100%">trophoblastic disease</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">1993</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://dx.doi.org/10.1002/zoo.1430120307</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">299–305</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Until now, the occurrence of hydatidiform mole in non-human primates has not been documented. This report presents a case in which a stillborn fetus, associated with a partial hydatidiform mole, was found at necropsy in the uterus of a pregnant chimpanzee (Pan troglodytes) which had suddenly died. Hydropic swelling of the chorionic villi and proliferation of trophoblastic cells were present. The trophoblast was stained enzyme-immunohistochemically with human chorionic gonadotropin (hCG) and pregnancy-specific-β1-glycoprotein (SP1). The concentrations of hCG and SP1 in maternal serum were high, 1,350 mIU/ml and 1,000 ng/ml, respectively. The distribution of DNA content of the cytotrophoblast in the molar villi shifted from diploid to an aneuploid pattern. © 1993 Wiley-Liss, Inc.&lt;/p&gt;
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