<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Macklon, N S</style></author><author><style face="normal" font="default" size="100%">Geraedts, J P M</style></author><author><style face="normal" font="default" size="100%">Fauser, B C J M</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Conception to ongoing pregnancy: the &#039;black box&#039; of early pregnancy loss.</style></title><secondary-title><style face="normal" font="default" size="100%">Hum Reprod Update</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Hum. Reprod. Update</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Abortion, Spontaneous</style></keyword><keyword><style  face="normal" font="default" size="100%">Aneuploidy</style></keyword><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Embryo, Mammalian</style></keyword><keyword><style  face="normal" font="default" size="100%">Endometrium</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Fertilization</style></keyword><keyword><style  face="normal" font="default" size="100%">Fertilization in Vitro</style></keyword><keyword><style  face="normal" font="default" size="100%">Gestational Age</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Pregnancy</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2002</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2002 Jul-Aug</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">333-43</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Even when conditions are optimal, the maximum chance of a clinically recognized pregnancy occurring in a given menstrual cycle is 30-40%. Increasing evidence points to preclinical pregnancy loss rather than failure of conception as the principal cause for the relatively low fecundity observed in humans. While sensitive assays for hCG have provided a glimpse of the events occurring between implantation and the missed menstrual period, new cytogenetic techniques have further opened this &#039;black box&#039;, providing novel insights into the causes of early pregnancy wastage. In this article, the evidence and causes of preclinical or &#039;occult&#039; pregnancy are reviewed, and the implications for the infertile patient are addressed.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><custom1><style face="normal" font="default" size="100%">&lt;p&gt;http://www.ncbi.nlm.nih.gov/pubmed/12206468?dopt=Abstract&lt;/p&gt;
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