<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Leckman, J F</style></author><author><style face="normal" font="default" size="100%">Goodman, W K</style></author><author><style face="normal" font="default" size="100%">North, W G</style></author><author><style face="normal" font="default" size="100%">Chappell, P B</style></author><author><style face="normal" font="default" size="100%">Price, L H</style></author><author><style face="normal" font="default" size="100%">Pauls, D L</style></author><author><style face="normal" font="default" size="100%">Anderson, G M</style></author><author><style face="normal" font="default" size="100%">Riddle, M A</style></author><author><style face="normal" font="default" size="100%">McDougle, C J</style></author><author><style face="normal" font="default" size="100%">Barr, L C</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The role of central oxytocin in obsessive compulsive disorder and related normal behavior.</style></title><secondary-title><style face="normal" font="default" size="100%">Psychoneuroendocrinology</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Psychoneuroendocrinology</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Behavior, Animal</style></keyword><keyword><style  face="normal" font="default" size="100%">Brain</style></keyword><keyword><style  face="normal" font="default" size="100%">Brain Mapping</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Hypothalamus</style></keyword><keyword><style  face="normal" font="default" size="100%">Neural Pathways</style></keyword><keyword><style  face="normal" font="default" size="100%">Neurophysins</style></keyword><keyword><style  face="normal" font="default" size="100%">Obsessive-Compulsive Disorder</style></keyword><keyword><style  face="normal" font="default" size="100%">Oxytocin</style></keyword><keyword><style  face="normal" font="default" size="100%">Stereotyped Behavior</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">1994</style></year></dates><volume><style face="normal" font="default" size="100%">19</style></volume><pages><style face="normal" font="default" size="100%">723-49</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Oxytocin (OT) is a neurosecretory nonapeptide synthesized in hypothalamic cells, which project to widely distributed sites in the CNS as well as the neurohypophysis. Central OT affects a variety of cognitive, grooming, affiliative, sexual, and reproductive behaviors in animals. Obsessive Compulsive Disorder (OCD) includes a range of cognitive and behavioral symptoms that bear some relationship to dimensions of behavior associated with OT. Anecdotal data and a recently completed cerebrospinal fluid (CSF) study provide evidence that some forms of OCD are related to OT dysfunction. Based on these findings, we hypothesize: 1) that some forms of OCD are at the extreme end of a range of normal behaviors that are mediated by OT and related systems; and that 2) some normal cognitive, affiliative, and sexual behaviors contain elements that are similar to features of OCD. Alternative hypotheses are considered, and a series of predictions are presented concerning the relationship between central OT and the onset, course, treatment response, and response to challenge procedures seen in this form of OCD.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">8</style></issue><custom1><style face="normal" font="default" size="100%">&lt;p&gt;http://www.ncbi.nlm.nih.gov/pubmed/7991761?dopt=Abstract&lt;/p&gt;
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