Genetics

MOCA Domain Leaders: 

This Domain lists topics dealing with inherited variation in living organisms, and some of the genetic processes responsible for this.

Domain Topics
Topic Name Topic Authors
ABCB10 (ATP-binding cassette, subfamily B (MDR/TAP) member 10) Majesta O'Bleness, James Sikela
ABO (ABO blood group ) Majesta O'Bleness, James Sikela
AHI1 (Abelson Helper Integration Site 1 ) Majesta O'Bleness
AMY1A (amylase, alpha 1A) Majesta O'Bleness, James Sikela
APOC1 (apolipoprotein C-I) Majesta O'Bleness, James Sikela
APOE (apolipoprotein E) Caleb Finch
AQP7 (aquaporin 7) Laura Dumas, James Sikela
AR (Androgen receptor) Majesta O'Bleness, James Sikela
ARHGAP11B (Rho GTPase Activating Protein 11B) Majesta O'Bleness
ARHGEF5 (Rho guanine nucleotide exchange factor (GEF) 5) Majesta O'Bleness, James Sikela
ASPM (asp (abnormal spindle) homolog, microcephaly associated) Majesta O'Bleness, James Sikela
C20orf203 (chromosome 20 open reading frame 203) Majesta O'Bleness, James Sikela
C22orf45 (Chromosome 22 open reading frame 45) Majesta O'Bleness, James Sikela
CASC5 (Cancer Susceptibility Candidate 5 ) Majesta O'Bleness
CASP12 (caspase-12 gene/pseudogene) Majesta O'Bleness, James Sikela
CCL3L1 (chemokine (C-C motif) ligand 3-like 1) Majesta O'Bleness, James Sikela
CDH12 (cadherin 12, type 2 (N-cadherin 2) ) Majesta O'Bleness, James Sikela
CDK5RAP2 (CDK5 regulatory subunit-associated protein 2) Majesta O'Bleness, James Sikela
CHRFAM7A (CHRNA7 (cholinergic receptor, nicotinic, alpha 7) and FAM7A (family with sequence similarity 7A) fusion) Majesta O'Bleness, James Sikela
CHRM3 (Cholinergic receptor, muscarinic 3) Majesta O'Bleness, James Sikela
CKB (Creatine kinase brain) Majesta O'Bleness, James Sikela
CLLU1 (Chronic lymphocytic leukemia up-regulated 1) Majesta O'Bleness, James Sikela
CMAH (cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase) pseudogene) Ajit Varki
COX5A (cytochrome c oxidase subunit Va) Lawrence Grossman
DCHS1 (Dachsous Cadherin-Related 1) Majesta O'Bleness
DDX11L (DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 like) Majesta O'Bleness, James Sikela
DNAH10OS (Dynein, axonemal heavy chain 10 opposite strand) Majesta O'Bleness, James Sikela
DRD4 (dopamine receptor D4) Majesta O'Bleness, James Sikela
DRD5 (Dopamine receptor D5) Majesta O'Bleness, James Sikela
DUSP22 (Dual specificity phosphatase 22) Majesta O'Bleness, James Sikela
DUX4 (double homeobox 4) Majesta O'Bleness, James Sikela
E2F6 (E2F transcription factor 6) Majesta O'Bleness, James Sikela
EDAR (ectodysplasin A receptor) Majesta O'Bleness
ELN (elastin) Majesta O'Bleness, James Sikela
FCGR1A (Fc fragment of IgG, high affinity Ia, receptor (CD64)) Majesta O'Bleness, James Sikela
FGFR2 (fibroblast growth factor receptor 2) Matthew Boisvert, Majesta O'Bleness, James Sikela
FOXP2 (forkhead box P2) Naruya Saitou
FRMPD2 (FERM and PDZ domain containing 2) Majesta O'Bleness, James Sikela
FSHR (Follicle-stimulating hormone receptor) Majesta O'Bleness, James Sikela
FZD8 (frizzled 8) Majesta O'Bleness
GADD45G (Growth arrest and DNA-damage-inducible protein 45 gamma) Majesta O'Bleness, James Sikela
GLRA4 (Glycine receptor, alpha 4) Majesta O'Bleness, James Sikela
GRIN3A (Glutamate receptor, ionotropic, N-methyl-D-aspartate 3A) Majesta O'Bleness, James Sikela
GRIN3B (Glutamate receptor, ionotropic, N-methyl-D-aspartate 3B) Majesta O'Bleness, James Sikela
GTF2H2 (General transcription factor IIH, polypeptide 2, 44kDa) Majesta O'Bleness, James Sikela
GTF2IRD2 (GTF2I repeat domain containing 2) Majesta O'Bleness, James Sikela
HAR1 (human accelerated region 1) Majesta O'Bleness, James Sikela
HLA-DRB1*11 (major histocompatibility complex, class II, DR beta 1 allele 11 ) Majesta O'Bleness, James Sikela
HYDIN (Hydrocephalus inducing homolog) Majesta O'Bleness, James Sikela
KIR3DL1 (killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1) Majesta O'Bleness, James Sikela
KRT41P (keratin 41 pseudogene) Majesta O'Bleness, James Sikela
LEPR (Leptin receptor) Majesta O'Bleness, James Sikela
MBL1P (mannose-binding lectin (protein A) 1, pseudogene) Majesta O'Bleness, James Sikela
MC1R (melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) ) Majesta O'Bleness, James Sikela
MCPH1 (microcephalin 1) Majesta O'Bleness, James Sikela
MHC Class I Majesta O'Bleness, James Sikela
MOXD2P (monooxygenase, DBH-like 2, pseudogene ) Majesta O'Bleness, James Sikela
MRC1 (Mannose receptor, C type 1) Majesta O'Bleness, James Sikela
MYH16 (myosin, heavy chain 16 pseudogene) Naruya Saitou
NAIP (NLR family, apoptosis inhibitory protein ) Majesta O'Bleness, James Sikela
NBPF15 (neuroblastoma breakpoint family, member 15) Majesta O'Bleness, James Sikela
NCF1 (Neutrophil cytosolic factor 1) Majesta O'Bleness, James Sikela
OCLN (Occludin) Majesta O'Bleness, James Sikela
OR4F17 (olfactory receptor, family 4, subfamily F, member 17) Majesta O'Bleness, James Sikela
PAK2 (p21 activated kinase 2) Majesta O'Bleness, James Sikela
PCDH11XY (protocadherin 11 X Y linked) Tim Crow, Majesta O'Bleness, James Sikela
PDE4DIP (Phosphodiesterase 4D interacting protein) Majesta O'Bleness, James Sikela
PDYN (prodynorphin) Majesta O'Bleness, James Sikela
PTPN20A (Protein tyrosine phosphatase, non-receptor type 20A) Majesta O'Bleness, James Sikela
RAB3IP (RAB3A interacting protein) Majesta O'Bleness, James Sikela
RGS6 (Regulator of G-protein signaling 6) Majesta O'Bleness, James Sikela
RLN (relaxin) Majesta O'Bleness, James Sikela
S100A7 (S100 calcium binding protein A7) Majesta O'Bleness, James Sikela
SERF1A (Small EDRK-rich factor 1A) Majesta O'Bleness, James Sikela
SERPINA13 (Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 13) Majesta O'Bleness, James Sikela
SIGLEC1 (sialic acid binding Ig-like lectin 1, sialoadhesin) Ajit Varki
SIGLEC11 (sialic acid binding Ig-like lectin 11) Ajit Varki
SIGLEC12 (sialic acid binding Ig-like lectin 12) Ajit Varki
SIGLEC13 (sialic acid binding Ig-like lectin 13) Ajit Varki
SIGLEC14 (sialic acid binding Ig-like lectin 14) Ajit Varki
SIGLEC16 (sialic acid binding Ig-like lectin 16) Ajit Varki
SIGLEC5 (sialic acid binding Ig-like lectin 5 ) Ajit Varki
SIGLEC6 (sialic acid binding Ig-like lectin 6) Ajit Varki
SIGLEC7 (sialic acid binding Ig-like lectin 7 ) Ajit Varki
SIGLEC9 (sialic acid binding Ig-like lectin 9) Ajit Varki
SLC2A1 (Solute carrier family 2 (facilitated glucose transporter) member 1) Majesta O'Bleness, James Sikela
SLC2A4 (Solute carrier family 2 (facilitated glucose transporter) member 4) Majesta O'Bleness, James Sikela
SLC6A8 (solute carrier family 6 (neurotransmitter transporter, creatine), member 8) Majesta O'Bleness, James Sikela
SMN1 (Survival of motor neurone 1) Majesta O'Bleness, James Sikela
SMN2 (Survival of motor neurone 2) Majesta O'Bleness, James Sikela
SPANXB (SPANX family, member B) Majesta O'Bleness, James Sikela
SPANXC (SPANX family, member C) Majesta O'Bleness, James Sikela
SRGAP2 (SLIT-ROBO Rho GTPase activating protein 2) Majesta O'Bleness, James Sikela
TAS2R38 (taste receptor, type 2, member 38) Majesta O'Bleness, James Sikela
TBC1D3 (TBC domain family, member 3) Majesta O'Bleness, James Sikela
TDG (Thymine-DNA glycosylase) Majesta O'Bleness, James Sikela
TDH (L-threonin dehydrogenase) Majesta O'Bleness, James Sikela
TH (tyrosine hydroxylase) Landon Klein
THBS4 (Thrombospondin 4) Majesta O'Bleness, James Sikela
TRGV10 (T cell receptor gamma variable 10) Majesta O'Bleness, James Sikela
TTR (transthyretin) MOCA Author
UOX (urate oxidase, pseudogene) Majesta O'Bleness, James Sikela
ZNF322 (Zinc finger protein 322) Majesta O'Bleness, James Sikela