| Anonymous | |
|---|---|
| Log in for more site access. | |
![]() | |
Cholera
Cholera is caused by the bacterium Vibrio cholerae, which secretes a toxin whose B subunit binds the cell surface ganglioside GM1, delivering a toxic A subunit to the interior of the intestinal cell, causing watery diarrhea. The famous bacteriologist Robert Koch found that he could not infect any other animals with the organism, and concluded that "...although these experiments were constantly repeated with material from fresh cholera cases, our mice remained healthy. We then made experiments on monkeys, cats, poultry, dogs and various other animals that we were able to get a hold of, but we never were able to arrive at anything in animals similar to the cholera". The reasons for this are unknown. There are statements in the literature that chimpanzees are also resistant to cholera.

