Home » MOCA » Domains » Novel Chromosome Features and Banding Patterns

Chromatin-Stained Banding Patterns

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Human Uniqueness Compared to "Great Apes": 
Absolute Difference
MOCA Domain: 
Novel Chromosome Features and Banding Patterns
MOCA Topic Authors: 
Veronica Searles
James Sikela

Chromosome banding employs multiple techniques such as Giemsa (G), reverse (R), centromere (C), and quinacrine (Q) banding to dye chromosomes during mitosis. Humans have unique constitutive heterochromatin (C-band) patterns, with novel C bands on the long arm of chromosome Y and in the pericentric regions of chromosomes 1, 9 and 16. Smaller C bands shared with non-human primates are found at the centromere of each chromosome and on the p arms of chromosomes 13, 14, 15, 21 and 22.

Related MOCA Topics
Related Topics:
TitleCertainty
Expansion and Redistribution of Heterochromatin True
Novel Features in Chromosome YTrue
Referenced By:
TitleCertainty
Amplification of Short Tandem RepeatsLikely
The Human Difference: 

Constitutive heterochromatin expansion
Centromeric expansion

References: 

Muller S and Windberg J (2001). Barcoding primate genomes: cytogenetic screening. Hum Genet 109:85-94.

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