Psoriasis

Certainty Style Key

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True Likely Speculative

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Human Uniqueness Compared to "Great Apes":

Likely Difference

MOCA Domain:

Medical Disease

MOCA Topic Authors:

Ajit Varki

Psoriasis is a chronic skin condition affecting about 2% of the human population, typically associated with raised, demarcated, red sking patches that have silvery scales over them. While the underlying cause is unknown there is evidence for a immune reaction, with a prominent contribution of T cells. The disease appears to be very rare in great apes.

Related Topics:

Title	Certainty
Autoimmune Disorders	Speculative
Bronchial Asthma	Speculative
Cleanliness	Speculative
Hairlessness	Speculative
Response to Tuberculin Test	Speculative
Rheumatoid Arthritis	Speculative
Siglec Expression on T Cells	Speculative
T Cell Reactivity	Likely

Timing

Timing of Appearance of the Difference in the Hominin Lineage.

For this entry assume that

the common ancestor of humans and old world monkeys was 25000 thousand (25 million) years ago
the common ancestor of humans and chimpanzees was 6000 thousand (6 million) years ago
the emergence of the genus Homo was 2000 thousand (2 million) years ago
the common ancestor of modern humans was 100 thousand years ago

Possible Appearance:

6000 Thousand Years

Probable Appearance:

200 Thousand Years

Definite Appearance:

100 Thousand Years

References:

[Psoriasis in a female chimpanzee] Biella U, Haustein UF, Seifert S, Adler J, Schüppel KF, Eulenberger K.Hautarzt. 1991 May;42(5):322-3. German.
Psoriasis. Nestle FO, Kaplan DH, Barker J. N Engl J Med. 2009 Jul 30;361(5):496-509.

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