SERPINA13 (Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 13)

Serpin peptidase inhibitor, clade A, member 13 (SERPINA13) is a human pseudogene in the Serpin family of proteins, which are involved in regulation of many diverse biological pathways such as blood coagulation, inflammation, and tumor suppression. In human, a nucleotide change has resulted in a premature stop codon in the 4th of 5 exons encoded, which has rendered this gene non-functional. Ramifications for the pseudogenization of SERPINA13 are not understood as the function of this gene in other primates is not known, although the mRNA for this gene is still expressed in human liver and thus may have played a role in liver function.