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SIGLEC13 (sialic acid binding Ig-like lectin 13)

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Human Uniqueness Compared to "Great Apes": 
Absolute Difference
MOCA Domain: 
Genetics
MOCA Topic Authors: 
Ajit Varki

The gene for Siglec-13 was specifically deleted in humans. The significance of this deletion is unknown and its expression in chimpanzees is currently being investigated.

Type of Human-Specific Changes in SIGLEC13
Gene Deletion

 

Related MOCA Topics
Related Topics:
TitleCertainty
Small/Large Intestine Length RatioSpeculative
Timing

Timing of Appearance of the Difference in the Hominin Lineage.

For this entry assume that

  • the common ancestor of humans and old world monkeys was 25000 thousand (25 million) years ago
  • the common ancestor of humans and chimpanzees was 6000 thousand (6 million) years ago
  • the emergence of the genus Homo was 2000 thousand (2 million) years ago
  • the common ancestor of modern humans was 100 thousand years ago

 

Probable Appearance: 
2000 Thousand Years
Definite Appearance: 
100 Thousand Years