Sarcoidosis

Sarcoidosis is a relatively uncommon disease in humans, and clinically manifests with hilar lymphadenopathy or lung involvement by non-caseating granulomas. The disease is seen more frequently in southeastern United States but has been reported in different countries. The etiology is still unclear although there is some evidence that it is a disease of disordered immune regulation in genetically predisposed individuals exposed to certain environmental agents. Sarcoidosis  has not yet been described in non-human primates.