a1varki

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Ajit Varki
Bio

Ajit Varki is currently Distinguished Professor in the Departments of Medicine and Cellular & Molecular Medicine, Co-Director of CARTA, Co-Director of the Glycobiology Research and Training Center, and Associate Dean for Physician-Scientist Training at the University of California, San Diego (UCSD). He received basic training in Physiology, Medicine, Biology, and Biochemistry at the Christian Medical College, Vellore, The University of Nebraska, and Washington University in St. Louis. He also has formal training and board certification in internal medicine, hematology, and oncology.  Dr. Varki is Executive Editor of the textbook "Essentials of Glycobiology" and is recipient of a MERIT award from the NIH, and an American Cancer Society Faculty Research Award.  He is an elected member of the American Academy of Arts and Sciences, The Insitute of Medicine of the National Academies, the American Society for Clinical Investigation, and the Association of American Physicians. Significant past appointments include: Co-Head, UCSD Division of Hematology-Oncology (1987-89); President of the Society for Glycobiology (1996); Editor-in-Chief of the Journal of Clinical Investigation (1992-97); the Interim Directorship of the UCSD Cancer Center (1996-1997), and President of the American Society for Clinical Investigation (1998-1999).  Dr. Varki's research interests are focused on a family of cell surface sugars called the Sialic Acids, and their roles in biology, evolution and disease. Currently active projects are relevant to the roles of sialic acids in microbial infectivity, the regulation of the immune response, the progression and spread of tumors, and, unique aspects of human evolution.  His group is particularly intrigued in finding multiple differences in sialic acid biology between humans and our closest evolutionary cousins, the great apes.  These differences are a signature of the events that occurred during the last few million years of human evolution, and may be relevant to understanding several aspects of the current human condition, both in health and disease.

URL
http://cmm.ucsd.edu/varki/

MOCA Domains

Listed here are the MOCA domains with which this user account is associated in addition to the type of involvement (Editor and/or Leader).

DomainInvolvement
Anatomy and BiomechanicsEditor
Cell Biology and BiochemistryLeader
EndocrinologyEditor
GeneticsEditor
GenomicsEditor
ImmunologyLeader
Medical DiseaseEditor
Organ PhysiologyEditor
PathologyEditor
PharmacologyEditor
Skin Biology and DiseaseLeader

MOCA Topics

Listed here are the MOCA topics for which this user account is one of the authors.

TopicDomain
Absolute Lymphocyte CountPathology
Absolute Neutrophil CountPathology
Alpha2-6-linked Sialic Acid ExpressionCell Biology and Biochemistry
CholeraMedical Disease
CMAH (cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase) pseudogene)Genetics
Female Iron Deficiency Medical Disease
Fibrosing Cardiomyopathy Medical Disease
Foamy Virus (Spumavirus) Infection Medical Disease
Hepatic Amyloidosis Medical Disease
HIV Progression to AIDS Medical Disease
Influenza A Infection Medical Disease
Malaria Medical Disease
Meningococcal Meningitis Medical Disease
Menstrual Blood LossReproductive Biology and Disease
Myocardial Infarction (Atherosclerotic Coronary Thrombosis) Medical Disease
N-Glycolylneuraminic Acid Expression Cell Biology and Biochemistry
PsoriasisMedical Disease
RBC and Serum FolatePathology
Response to Tuberculin Test Immunology
Salmonella Typhi Infection Severity Medical Disease
Serum Vitamin B12/B12 Binding CapacityPathology
Sexually Transmitted Bacterial Diseases Medical Disease
Sialic Acid Recognition by Siglecs Immunology
Sialic Acid-expressing PathogensMedical Disease
Sialoadhesin on Macrophages Immunology
Siglec Expression in MicrogliaNeuroscience
Siglec Expression on T Cells Immunology
SIGLEC1 (sialic acid binding Ig-like lectin 1, sialoadhesin)Genetics
SIGLEC11 (sialic acid binding Ig-like lectin 11)Genetics
SIGLEC12 (sialic acid binding Ig-like lectin 12)Genetics
SIGLEC13 (Siglec-13)Genetics
SIGLEC14 (Siglec-14)Genetics
SIGLEC16 (Siglec-16)Genetics
SIGLEC5 (sialic acid binding Ig-like lectin 5 )Genetics
SIGLEC6 (sialic acid binding Ig-like lectin 6)Genetics
SIGLEC7 (sialic acid binding Ig-like lectin 7 )Genetics
SIGLEC9 (sialic acid binding Ig-like lectin 9)Genetics
T Cell Reactivity Immunology
Thyroid Hormone Metabolism Endocrinology
TTR (transthyretin)Genetics
Viral Hepatitis Complications Medical Disease
Wound HealingSkin Biology and Disease