Cancer

Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer.

Forsberg, LA, Rasi, C, Malmqvist, N, Davies, H, Pasupulati, S, Pakalapati, G, Sandgren, J, de Ståhl, TDiaz, Zaghlool, A, Giedraitis, V, Lannfelt, L, Score, J, Cross, NCP, Absher, D, Janson, ETiensuu, Lindgren, CM, Morris, AP, Ingelsson, E, Lind, L, Dumanski, JP. Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer. Nat Genet. 2014;46(6):624-8.

The architecture and evolution of cancer neochromosomes.

Garsed, DW, Marshall, OJ, Corbin, VDA, Hsu, A, Di Stefano, L, Schröder, J, Li, J, Feng, Z, Kim, BW, Kowarsky, M, Lansdell, B, Brookwell, R, Myklebost, O, Meza-Zepeda, L, Holloway, AJ, Pedeutour, F, Choo, KHAndy, Damore, MA, Deans, AJ, Papenfuss, AT, Thomas, DM. The architecture and evolution of cancer neochromosomes. Cancer Cell. 2014;26(5):653-67.

Cell cycle, oncogenic and tumor suppressor pathways regulate numerous long and macro non-protein-coding RNAs.

Hackermüller, J, Reiche, K, Otto, C, Hösler, N, Blumert, C, Brocke-Heidrich, K, Böhlig, L, Nitsche, A, Kasack, K, Ahnert, P, Krupp, W, Engeland, K, Stadler, PF, Horn, F. Cell cycle, oncogenic and tumor suppressor pathways regulate numerous long and macro non-protein-coding RNAs. Genome Biol. 2014;15(3):R48.

Human and Helicobacter pylori coevolution shapes the risk of gastric disease.

Kodaman, N, Pazos, A, Schneider, BG, M Piazuelo, B, Mera, R, Sobota, RS, Sicinschi, LA, Shaffer, CL, Romero-Gallo, J, de Sablet, T, Harder, RH, Bravo, LE, Peek, RM, Wilson, KT, Cover, TL, Williams, SM, Correa, P. Human and Helicobacter pylori coevolution shapes the risk of gastric disease. Proc Natl Acad Sci U S A. 2014;111(4):1455-60.

Simultaneous purifying selection on the ancestral MC1R allele and positive selection on the melanoma-risk allele V60L in south Europeans.

Martínez-Cadenas, C, López, S, Ribas, G, Flores, C, García, O, Sevilla, A, Smith-Zubiaga, I, Ibarrola-Villaba, M, Pino-Yanes, Mdel Mar, Gardeazabal, J, Boyano, D, de Galdeano, AGarcía, Izagirre, N, de la Rúa, C, Alonso, S. Simultaneous purifying selection on the ancestral MC1R allele and positive selection on the melanoma-risk allele V60L in south Europeans. Mol Biol Evol. 2013;30(12):2654-65.
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