Malignant malaria in humans

Malaria, which is caused by parasitic protozoa and spread by mosquitos, remains a devasting infectious disease that endangers 40% of the world’s population.  In 2018 there were almost with almost a quarter billion annual cases and a half million deaths.  However, before the discovery of antimalarial treatments, is estimated that, up to 20% of children would have died from malaria, putting strong selective on the human genome.  I will discuss how many modern humans carry genetic signatures that reveal a life and death struggle with malaria.