Keywords: Animals, Biological Evolution, Bone and Bones, Chromatin, DNA Damage, DNA Methylation, Epigenesis, Genetic, Genome, Human, Hair, Humans, Transcription, Genetic

Abstract:

[Perspective article]

Over the past 30 years, ancient DNA has helped to track past population dynamics, environmental changes, and historical epidemics. Studies of ancient genomes have provided insights into the evolution of humans (1, 2) and other mammals (3). Going beyond sequences, epigenetic changes, such as methylation patterns, can also be detected in ancient genomes (4, 5). This epigenetic information has the potential to elucidate regulatory changes underlying species divergence and population adaptation.

Notes:

http://www.sciencemag.org/content/345/6196/511.full

URL: http://www.ncbi.nlm.nih.gov/pubmed/25082684

DOI: 10.1126/science.1256515

Custom 1:

http://www.ncbi.nlm.nih.gov/pubmed/25082684?dopt=Abstract

Alternate Journal: Science

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