Functional primate genomics—leveraging the medical potential

Bibliographic Collection: 
CARTA-Inspired Publication
Publication Type: Journal Article
Authors: Enard, W
Year of Publication: 2012
Journal: Journal of molecular medicine
Publication Language: eng
Abstract:

Abstract Within biomedicine, comparative genomics is crucial for interpreting human genetic variants and building proper animal models. As our closest relatives, primates are of particular relevance in this frame work. Here, I review principles and concrete examples of this approach. Since one can expect that generating the necessary genomic DNA sequences will not be the major limiting factor in the near future, I argue that in analogy to …

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Times cited: 17

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