Genetic mapping of brain plasticity in Williams Syndrome: ERP markers of face and language processing across development
In Williams Syndrome (WS), a known genetic deletion results in atypical brain function with strengths in face and languageprocessing. We examined how genetic influences on brain activity change with development. In three studies, event-related potentials (ERPs) from large samples of children, adolescents, and adults with the full genetic deletion for WS were compared to typically developing controls, and two adults with partial deletions for WS. Studies 1 and 2 identified ERP markers of brainplasticity in WS across development. Study 3 suggested that, in adults with partial deletions for WS, specific genes may be differentially implicated in face and language processing.
PMC3695384