The origin of human chromosome 18 from a human/ape ancestor.

Bibliographic Collection:

MOCA Reference, APE

Publication Type: Journal Article

Authors: McConkey, E H

Year of Publication: 1997

Journal: Cytogenet Cell Genet

Volume: 76

Issue: 3-4

Pagination: 189-91

Date Published: 1997

Publication Language: eng

ISSN: 0301-0171

Keywords: Animals, Chromosomes, Human, Pair 18, Hominidae, Humans, In Situ Hybridization, Fluorescence

Abstract:

Karyotype analysis by previous investigators demonstrated that human chromosome 18 differs from homologous chromosomes in the great apes by a pericentric inversion. The present study uses fluorescence in situ hybridization on human and pygmy chimpanzee chromosomes to confirm the inversion and to delimit the regions where the breakpoints must have occurred in the human/ape ancestor.

Custom 1:

http://www.ncbi.nlm.nih.gov/pubmed/9186521?dopt=Abstract

Alternate Journal: Cytogenet. Cell Genet.

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