Up-regulation of the human-specific CHRFAM7A gene in inflammatory bowel disease

Bibliographic Collection: 
CARTA-Inspired Publication
Publication Type: Journal Article
Authors: Baird, Andrew; Coimbra, Raul; Dang, Xitong; Eliceiri, Brian P; Costantini, Todd W
Year of Publication: 2016
Journal: BBA Clinical
Publisher: Elsevier
Publication Language: eng
ISBN Number: 2214-6474
Abstract:

Background: The α7-subunit of the α7-nicotinic acetylcholine receptor (α7-nAChR) is an obligatory intermediate for the anti-inflammatory effects of the vagus nerve. But in humans, there exists a second gene called CHRFAM7A that encodes a dominant negative α7- ...

DOI: 10.1016/j.bbacli.2015.12.003
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