Representation of numerical and sequential patterns in macaque and human brains.

Bibliographic Collection: 
Publication Type: Journal Article
Authors: Wang, Liping; Uhrig, Lynn; Jarraya, Bechir; Dehaene, Stanislas
Year of Publication: 2015
Journal: Curr Biol
Volume: 25
Issue: 15
Pagination: 1966-74
Date Published: 2015 Aug 3
Publication Language: eng
ISSN: 1879-0445
Keywords: Adult, Animals, Auditory Perception, Brain, Brain Mapping, Female, Humans, Macaca mulatta, Magnetic Resonance Imaging, Male, Middle Aged, Young Adult

The ability to extract deep structures from auditory sequences is a fundamental prerequisite of language acquisition. Using fMRI in untrained macaques and humans, we investigated the brain areas involved in representing two abstract properties of a series of tones: total number of items and tone-repetition pattern. Both species represented the number of tones in intraparietal and dorsal premotor areas and the tone-repetition pattern in ventral prefrontal cortex and basal ganglia. However, we observed a joint sensitivity to both parameters only in humans, within bilateral inferior frontal and superior temporal regions. In the left hemisphere, those sites coincided with areas involved in language processing. Thus, while some abstract properties of auditory sequences are available to non-human primates, a recently evolved circuit may endow humans with a unique ability for representing linguistic and non-linguistic sequences in a unified manner.

DOI: 10.1016/j.cub.2015.06.035
Alternate Journal: Curr. Biol.