Myocardial Infarction (Atherosclerotic Coronary Thrombosis)

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Human Uniqueness Compared to "Great Apes": 
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One of the commonest causes of death in humans is the classic “heart attack”, which is caused by blockade of a major coronary blood vessel supplying oxygen to the heart muscle. The usual cause is partial blockage of the coronary blood vessel by an atherosclerotic plaque, frequently complicated by plaque rupture and/or local thrombosis. While great apes can develop atherosclerotic vascular disease, symptomatic atherosclerotic coronary thrombosis appears to be almost non-existent. This is somewhat surprising given that chimpanzees generally have higher blood cholesterol levels than humans. Meanwhile, chimpanzees and other "great apes" suffer from a interstitial myocardial fibrosis that is uncommon in humans.

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Fibrosing Cardiomyopathy Speculative

References

  1. Gut microbiome composition is associated with cardiac disease in zoo-housed western lowland gorillas (Gorilla gorilla gorilla)., Krynak, Katherine L., Burke David J., Martin Ryan A., and Dennis Patricia M. , FEMS Microbiol Lett, 2017 Aug 15, Volume 364, Issue 15, (2017)
  2. Physical activity patterns and biomarkers of cardiovascular disease risk in hunter-gatherers, Raichlen, David A., Pontzer Herman, Harris Jacob A., Mabulla Audax Z. P., Marlowe Frank W., J. Snodgrass Josh, Eick Geeta, J. Berbesque Colette, Sancilio Amelia, and Wood Brian M. , American Journal of Human BiologyAm. J. Hum. Biol., 2016, p.n/a - n/a, (2016)