Organization of Layer 4A of Area V1
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Layer 4A of the primary visual area (V1; area 17; striate cortex) has a distinctive organization in humans: a meshwork of neurons and neurites that express markers for the magnocellular visual pathway (Cat-301, nonphosphorylated neurofilament protein (NPNF), microtubule-associated protein 2 (MAP2)), embedded within which are clusters of small, calbindin-containing neurons. Chimpanzees, Old World monkeys, and New World monkeys do not exhibit significant expression of Cat-301 in layer 4A, and the organization of neurites expressing NPNF and MAP2 is different in nonhuman primates.
Human-specific organization of primary visual cortex: alternating compartments of dense Cat-301 and calbindin immunoreactivity in layer 4A., , Cereb Cortex, 07/2002, Volume 12, Issue 7, p.671-91, (2002)
Distinctive compartmental organization of human primary visual cortex., , Proc Natl Acad Sci U S A, 1999 Sep 28, Volume 96, Issue 20, p.11601-6, (1999)