Psoriasis

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True Likely Speculative

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Human Uniqueness Compared to "Great Apes":

Likely Difference

MOCA Domain:

Medical Disease

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Psoriasis is a chronic skin condition affecting about 2% of the human population, typically associated with raised, demarcated, red sking patches that have silvery scales over them. While the underlying cause is unknown there is evidence for a immune reaction, with a prominent contribution of T cells. The disease appears to be very rare in great apes.

Timing

Timing of appearance of the difference in the Hominin Lineage as a defined date or a lineage separation event. The point in time associated with lineage separation events may change in the future as the scientific community agrees upon better time estimates. Lineage separation events are defined in 2017 as:

the Last Common Ancestor (LCA) of humans and old world monkeys was 25,000 - 30,000 thousand (25 - 30 million) years ago
the Last Common Ancestor (LCA) of humans and chimpanzees was 6,000 - 8,000 thousand (6 - 8 million) years ago
the emergence of the genus Homo was 2,000 thousand (2 million) years ago
the Last Common Ancestor (LCA) of humans and neanderthals was 500 thousand years ago
the common ancestor of modern humans was 100 - 300 thousand years ago

Possible Appearance:

6,000 thousand years ago

Probable Appearance:

200 thousand years ago

Definite Appearance:

100 thousand years ago

Topic	Certainty
Autoimmune Disorders	Speculative
Bronchial Asthma	Speculative
Cleanliness	Speculative
Hairlessness	Speculative
Response to Tuberculin Test	Speculative
Rheumatoid Arthritis	Speculative
Siglec Expression on T Cells	Speculative
T Cell Reactivity	Likely

References

Psoriasis., Nestle, F. O., Kaplan D. H., and Barker J. , N Engl J Med, 07/2009, Volume 361, Issue 5, p.496-509, (2009)
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[Psoriasis in a female chimpanzee]., Biella, U, Haustein U F., Seifert S, Adler J, Schüppel K F., and Eulenberger K , Hautarzt, 05/1991, Volume 42, Issue 5, p.322-3, (1991)
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