Response to Tuberculin Test
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Tuberculin (an extract of mycobacterial cell walls) is used as a skin antigen challenge for testing tuberculosis exposure and sub-clinical infections in humans and captive great apes. Chimpanzees are said to require up to 10 times the dose of this antigen for a comparable positive reaction. This implies a reduction in the "delayed-type hypersensitivity" reaction, which involves several kinds of white blood cells, particularly T cells.
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