Sarcoidosis

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Sarcoidosis is a relatively uncommon disease in humans, and clinically manifests with hilar lymphadenopathy or lung involvement by non-caseating granulomas. The disease is seen more frequently in southeastern United States but has been reported in different countries. The etiology is still unclear although there is some evidence that it is a disease of disordered immune regulation in genetically predisposed individuals exposed to certain environmental agents. Sarcoidosis  has not yet been described in non-human primates.
  
 

Related MOCA Topics
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Title Certainty
MRC1 (Mannose receptor, C type 1) Likely

References

  1. Sarcoidosis., Baughman, Robert P., Lower Elyse E., and Bois Roland M. du , Lancet, 2003 Mar 29, Volume 361, Issue 9363, p.1111-8, (2003)