Uterine Adenomyosis and Endometriosis

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Endometriosis (i.e. the presence of endometrial  tissue outside of the uterine cavity, often in the pelvic abdomen, fallopian tube, and appendix) is a common condition in women and, because of pain during menstruation, can be disabling. Various theories  for its occurrence have been suggested and extensive work is proceeding in rodents and catarrhine primates (rhesus, baboon) to understand etiology and best therapy. Endometriosis is not uncommon in rhesus and baboon but has not been reported in apes.

Adenomyosis is the benign infiltration of the myometrium by endometrium. It is somewhat similar to endometriosis but it is generally painless and without major sequelae. Pelvic pain may also exist and there may be irregular uterine bleeding. It has also been reported in rhesus and baboon, and the first two cases in a chimpanzee were reported by Barrier et al., 2007


  1. Spontaneous adenomyosis in the chimpanzee (Pan troglodytes): a first report and review of the primate literature: case report., Barrier, Breton F., Allison Jana, Hubbard Gene B., Dick Edward J., Brasky Kathleen M., and Schust Danny J. , Hum Reprod, 2007 Jun, Volume 22, Issue 6, p.1714-7, (2007)
  2. Future directions in endometriosis research., D'Hooghe, Thomas M., Debrock Sophie, Meuleman Christel, Hill Joseph A., and Mwenda Jason M. , Obstet Gynecol Clin North Am, 2003 Mar, Volume 30, Issue 1, p.221-44, (2003)