Moving primate genomics beyond the chimpanzee genome
Bibliographic Collection:
CARTA-Inspired Publication
Publication Type: Journal Article
Authors: Goodman, M.; Grossman, L. I.; Wildman, D. E.
Year of Publication: 2005
Journal: Trends Genet
Volume: 21
Edition: 2005/07/13
Number: 9
Pagination: 511-7
Date Published: Sep
Type of Article: Research Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.Review
Publication Language: eng
ISBN Number: 0168-9525 (Print)0168-95
Accession Number: 16009448
Keywords: *Evolution, *Genetic Variation, *Genome, Animals, Computational Biology, Humans, Molecular, Pan troglodytes/genetics, Phylogeny, Primates/classification/*genetics
Abstract:
The comparative DNA sequence data that already exist on individual genomic loci depict the phylogenetic relationships of nearly all extant primate genera. Such a phylogenetic representation of the primates, validated by many sequenced primate genomes, and encompassing the full adaptive diversity of the order, is a prerequisite for identifying the genetic basis of humankind, and for testing the proposed human uniqueness of these traits. Some of these traits have been discovered recently, particularly in genes encoding proteins that are important for brain function.
Notes:
Trends Genet. 2005 Sep;21(9):511-7.
Alternate Journal: Trends in genetics : TIG
Author Address:
Department of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA. mgoodwayne@aol.com
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