Cholera transmission: the host, pathogen and bacteriophage dynamic.

Bibliographic Collection:

MOCA Reference, APE

Publication Type: Journal Article

Authors: Nelson, Eric J; Harris, Jason B; Morris, J Glenn; Calderwood, Stephen B; Camilli, Andrew

Year of Publication: 2009

Journal: Nat Rev Microbiol

Volume: 7

Issue: 10

Pagination: 693-702

Date Published: 2009 Oct

Publication Language: eng

ISSN: 1740-1534

Keywords: Animals, Bacteriophages, Cholera, Fresh Water, Humans, Vibrio cholerae, Zimbabwe

Abstract:

Zimbabwe offers the most recent example of the tragedy that befalls a country and its people when cholera strikes. The 2008-2009 outbreak rapidly spread across every province and brought rates of mortality similar to those witnessed as a consequence of cholera infections a hundred years ago. In this Review we highlight the advances that will help to unravel how interactions between the host, the bacterial pathogen and the lytic bacteriophage might propel and quench cholera outbreaks in endemic settings and in emergent epidemic regions such as Zimbabwe.

DOI: 10.1038/nrmicro2204

Custom 1:

http://www.ncbi.nlm.nih.gov/pubmed/19756008?dopt=Abstract

Alternate Journal: Nat. Rev. Microbiol.

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