CKB (Creatine kinase brain)
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Human Uniqueness Compared to "Great Apes":
Creatine kinase brain type (CKB) is a brain specific kinase that utilizes phosphocreatine to generate ATP. The expression of this gene is higher in the human brain than it is in other primates, which may provide more energy for use by the human brain from the phosphocreatine circuit. This availability of more energy to the brain has been hypothesized to play a role in the increased human brain size.
Comparative expression analysis of the phosphocreatine circuit in extant primates: Implications for human brain evolution., , J Hum Evol, 2011 Feb, Volume 60, Issue 2, p.205-12, (2011)