Certainty Style Key

Certainty styling is being phased out topic by topic.

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True   Likely   Speculative
Human Uniqueness Compared to "Great Apes": 
Likely Difference

The double homebox (DUX) family contains genes occurring in tandem at multiple regions of the genome, most commonly in areas of heterochromatic sequence. Many of these genes are involved in transcriptional regulation and are active during embryogenesis. An examination of DUX genes on chromosome Y demonstrated that a DUX gene cassette transposed to this chromosome and subsequently diverged, such that DUXY copies 2-4, which have a stop codon in chimpanzee that renders them non-functional, underwent neofunctionalization in the human lineage.

The Human Difference: 


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Related Topics (hover over title for reason):


  1. Complex evolution of a Y-chromosomal double homeobox 4 (DUX4)-related gene family in hominoids., Schmidt, Julia, Kirsch Stefan, Rappold Gudrun A., and Schempp Werner , PLoS One, 2009, Volume 4, Issue 4, p.e5288, (2009)