GRIN3B (Glutamate receptor, ionotropic, N-methyl-D-aspartate 3B)
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Glutamate receptor, ionotropic, N-methyl-D-aspartate 3A (GRIN3B) is a subunit of NMDA receptors, which are glutamate regulated ion-channels that regulate excitatory synaptic transmission. GRIN3B genetic changes have been associated with changes in social interaction and anxiety. GRIN3B has an amino acid change that lead to a gain of a phosphorylation site. Change in the human GRIN3B has been hypothesized to play a role in human higher brain function.