KIR3DL1 (killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1)
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Killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 (KIR3DL1) is involved in regulation of the development and response of natural killer cells and are essential parts of human immune defense. All KIR genes are located in the leukocyte receptor complex on chromosome 19q13.4. In humans, the KIR family of genes in subdivided into two haplotypes that evolved after the split with the common ancestor with chimp. KIR3DL1 is a member of the A-haplotype.
Variable NK cell receptors exemplified by human KIR3DL1/S1., , J Immunol, 07/2011, Volume 187, Issue 1, p.11-9, (2011)
Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus., , PLoS One, 2010, Volume 5, Issue 12, p.e15115, (2010)