SLC2A1 (Solute carrier family 2 (facilitated glucose transporter) member 1)
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Solute carrier family 2, member 1 (SLC2A1) is a major glucose transporter expressed in the mammalian brain. SLC2A1 shows HLS increased expression in the cerebral cortex as well as signs of positive selection. Given the protein’s role in sugar transport it is hypothesized it may play a role in the energy tradeoff between the brain and body required for increased brain to body ratio in humans.
A potential role for glucose transporters in the evolution of human brain size., , Brain Behav Evol, 2011, Volume 78, Issue 4, p.315-26, (2011)