Premature craniosynostosis-a complication of thyroid replacement therapy.

Bibliographic Collection:

MOCA Reference, APE

Publication Type: Journal Article

Authors: Penfold, J L; Simpson, D A

Year of Publication: 1975

Journal: J Pediatr

Volume: 86

Issue: 3

Pagination: 360-3

Date Published: 1975 Mar

Publication Language: eng

ISSN: 0022-3476

Keywords: Child, Congenital Hypothyroidism, Craniosynostoses, Female, Head, Humans, Hypothyroidism, Infant, Infant, Newborn, Male, Skull, Thyroxine

Abstract:

Three hypothyroid children with premature craniosynostosis are presented, who have been treated intensively with 1-thyroxine from early infancy. It is postulated that the craniosynostosis is the result of iatrogenic hyperthyroidism during a critical period of skull growth. Various regimens of treatment for hypothyroidism are discussed with recommendations for avoiding this potentially hazardous complication of therapy.

Custom 1:

http://www.ncbi.nlm.nih.gov/pubmed/1113223?dopt=Abstract

Alternate Journal: J. Pediatr.

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