My research and clinical work is directed toward understanding the cognitive and behavioural deficits of brain-injured children in relation to the underlying neuropathology. The goal is to develop new knowledge about the ontogeny of specific neural systems. Together with my colleagues, we have made a series of discoveries concerning the ontogenetic neural bases of episodic and semantic memory in developmental amnesia . Specifically, we have demonstrated three dissociations in cognitive memory, between episodic vs semantic memory, recognition vs recall, and familiarity vs recollection. Another area of research interest concerns the speech and language disorder associated with the FOXP2 gene mutation. Through the study of the three-generational KE family, we have identified the phenotype of verbal and orofacial dyspraxia resulting from abnormalities of the FOXP2, and have identified the structural and functional brain correlates of this inherited form of oromotor dyspraxia. Lastly, we have had a long standing interest in studying the effects of focal lesions on the organization and lateralization of function in the developing brain. We have studied groups of children with hemispherectomy, temporal lobectomy or frontal lobectomy with the goal of understanding the differences in capacity for functional reorganization in the developing brain as compared with that of the mature brain.