Systemic lupus erythematosus in a rhesus macaque.

Bibliographic Collection:

MOCA Reference, APE

Publication Type: Journal Article

Authors: Anderson, S T; Klein, E C

Year of Publication: 1993

Journal: Arthritis Rheum

Volume: 36

Issue: 12

Pagination: 1739-42

Date Published: 1993 Dec

Publication Language: eng

ISSN: 0004-3591

Keywords: Animals, Disease Models, Animal, Glomerulonephritis, Membranoproliferative, Kidney, Lupus Erythematosus, Systemic, Macaca mulatta, Male

Abstract:

We describe the clinical course and histopathologic findings in a rhesus macaque (Macaca mulatta) which developed a systemic inflammatory disorder resembling systemic lupus erythematosus (SLE). The manifestations of the SLE included antinuclear antibody, hemolytic anemia, membranoproliferative glomerulonephritis, and arthritis. To our knowledge, spontaneously occurring SLE has not previously been described in nonhuman primates.

Custom 1:

http://www.ncbi.nlm.nih.gov/pubmed/8250994?dopt=Abstract

Alternate Journal: Arthritis Rheum.

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