ABCB10 (ATP-binding cassette, subfamily B (MDR/TAP) member 10)
ATP-binding cassette, sub-family B (MDR/TAP), member 10 is a mitochondrial inner membrane ATP-binding cassette transporter which is highly expressed during erythroid maturation in hematopoietic tissues. Abcb10 interacts with Mfrn1 to promote Mfrn1-dependent mitochondrial iron importation. Array comparative genomic hybridization indicates that Abcb10 shows higher copy number in human than in any other primate. The significance of these copies in human is unknown.
Identification of human specific gene duplications relative to other primates by array CGH and quantitative PCR., , Genomics, 2010 Apr, Volume 95, Issue 4, p.203-9, (2010)
Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria., , Proc Natl Acad Sci U S A, 2009 Sep 22, Volume 106, Issue 38, p.16263-8, (2009)
Lineage-specific gene duplication and loss in human and great ape evolution., , PLoS Biol, 07/2004, Volume 2, Issue 7, p.E207, (2004)