CHRM3 (Cholinergic receptor, muscarinic 3)
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Human Uniqueness Compared to "Great Apes":
Cholinergic receptor, muscarinic 3 (CHRM3) is a G protein coupled receptor that is involved in the control of smooth muscle contraction. In humans, a L1HS transposon insertion has created a novel transcript that is the only CHRM3 transcript to be expressed in placenta. The significance of this new transcript is as of yet is unknown.
Identification of human-specific transcript variants induced by DNA insertions in the human genome., , Bioinformatics, 2011 Jan 1, Volume 27, Issue 1, p.14-21, (2011)
Gain of new exons and promoters by lineage-specific transposable elements-integration and conservation event on CHRM3 gene., , Mol Cells, 2009 Aug 31, Volume 28, Issue 2, p.111-7, (2009)