DDX11L (DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 like)
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DEAD/H box polypeptide 11-like gene (DDX11L) is a gene that propagated in the subtelomeric regions of the human genome. It is present and expressed from the subtelomeric regions of at least 14 chromosomes. Its precursor gene, DDX11, is a RNA helicase and is hypothesized to function in maintenance of chromosome transmission fidelity and genome stability. The ramifications of the copy number expansion of this gene in the human lineage is as of yet unknown.
Identification of human specific gene duplications relative to other primates by array CGH and quantitative PCR., , Genomics, 2010 Apr, Volume 95, Issue 4, p.203-9, (2010)
DDX11L: a novel transcript family emerging from human subtelomeric regions., , BMC Genomics, 2009, Volume 10, p.250, (2009)
Lineage-specific gene duplication and loss in human and great ape evolution., , PLoS Biol, 07/2004, Volume 2, Issue 7, p.E207, (2004)